Animal & veterinary · openFDA

Animal drug adverse event reports

Reports of adverse events in animals given veterinary drugs, by species, drug and reaction. 1,357,337 records; openFDA updated it 2026-09-23. About this dataset

Newest records

Most reported reactions
  • Vomiting213,498
  • Diarrhoea82,046
  • Lethargy (see also Central nervous system depression in 'Neurological')76,422
  • Emesis69,445
  • INEFFECTIVE, HEARTWORM LARVAE69,276
  • Lack of efficacy (ectoparasite) - flea63,352
  • Anorexia59,483
  • Lack of efficacy - NOS56,125
  • MSK

    Reactions: Lot # and/or Expiration date incorrect

    Unknown
  • MSK

    Cat · Reactions: Application site hair loss

    Animal Owner
  • MSK

    Dog · Reactions: Lack of efficacy (endoparasite) - heartworm, Intentional misuse, Inappropriate schedule of drug administration

    Other Health Care ProfessionalSerious
  • MSK

    Dog · Reactions: Lack of efficacy (endoparasite) - heartworm, Weight loss

    VeterinarianSerious
  • MSK

    Dog · Reactions: Lack of efficacy (bacteria) - Borrelia, Medication error NOS

    Other Health Care Professional
  • MSK

    Dog · Reactions: Lack of efficacy (endoparasite) - heartworm, Medication error NOS

    Other Health Care ProfessionalSerious
  • MSK

    Dog · Reactions: Lack of efficacy (bacteria) - Borrelia, Intentional misuse

    Other Health Care Professional
  • MSK

    Dog · Reactions: Ataxia, Difficulty going up/down stairs

    Other Health Care Professional
  • MSK

    Dog · Reactions: Seizure NOS

    Other Health Care ProfessionalSerious
  • MSK

    Reactions: Product label issues

    Animal Owner
  • MSK

    Reactions: Administration device NOS, abnormal

    Animal Owner
  • MSK

    Reactions: Containers, Leaking, Seal, Abnormal

    Other
  • MSK

    Dog · Reactions: Lack of efficacy (endoparasite) - hookworm, Medication error NOS

    Other Health Care ProfessionalSerious
  • MSK

    Dog · Reactions: Lack of efficacy (endoparasite) - roundworm NOS

    Other Health Care ProfessionalSerious
  • MSK

    Cat · Reactions: Foaming at the mouth, Dilated pupils

    Animal Owner
  • MSK

    Dog · Reactions: Vomiting

    Other Health Care Professional
  • MSK

    Dog · Reactions: Vomiting

    Veterinarian
  • MSK

    Dog · Reactions: Lack of efficacy (bacteria) - Borrelia

    Other Health Care Professional
  • MSK

    Cat · Reactions: Application site hair loss, Application site scab

    Animal Owner
  • MSK

    Reactions: Tablets, Abnormal

    Other
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How to read this: Each report says someone told FDA an event happened while a product was used. A report does not show the product caused it, and counts rise and fall with how many people report. Data from openFDA, FDA's public API. FDA says not to rely on it to make decisions about medical care and to treat every result as unvalidated; confirm against FDA's own record and the product labeling. Not medical or legal advice.