Animal & veterinary · openFDA

Animal drug adverse event reports

Reports of adverse events in animals given veterinary drugs, by species, drug and reaction. 1,378,854 records; openFDA updated it 2026-11-09. About this dataset

Newest records

Most reported reactions
  • Vomiting215,756
  • Diarrhoea83,314
  • Lethargy (see also Central nervous system depression in 'Neurological')76,433
  • Emesis69,533
  • INEFFECTIVE, HEARTWORM LARVAE69,277
  • Lack of efficacy (ectoparasite) - flea65,571
  • Anorexia59,808
  • Lack of efficacy - NOS57,453
  • MSK

    Dog · Reactions: Vomiting, Increased drinking, Medication error NOS

    Other Health Care Professional
  • MSK

    Cat · Reactions: Lack of efficacy (ectoparasite) - flea, Medication error NOS, Drug dose omission

    Other Health Care Professional
  • MSK

    Reactions: Appearance, Abnormal, Color, Abnormal

    Other Health Care Professional
  • MSK

    Dog · Reactions: Vomiting, Lethargy (see also Central nervous system depression in Neurological), Icterus +6

    VeterinarianSerious
  • MSK

    Dog · Reactions: Lack of efficacy (endoparasite) - heartworm

    VeterinarianSerious
  • MSK

    Dog · Reactions: Lack of efficacy (endoparasite) - heartworm

    Other Health Care ProfessionalSerious
  • MSK

    Dog · Reactions: Vomiting

    Animal Owner
  • MSK

    Dog · Reactions: Application site irritation

    Other Health Care Professional
  • MSK

    Dog · Reactions: Lack of efficacy (endoparasite) - heartworm

    Other Health Care ProfessionalSerious
  • MSK

    Reactions: Underfilling, Package

    Other
  • MSK

    Cat · Reactions: Application site hair loss, Application site scab

    Animal Owner
  • MSK

    Dog · Reactions: Excess tear flow, Hair coat discolouration, Lacrimal disorder NOS

    VeterinarianSerious
  • MSK

    Dog · Reactions: Lack of efficacy (endoparasite) - heartworm

    Other Health Care ProfessionalSerious
  • MSK

    Dog · Reactions: Vomiting, Lethargy (see also Central nervous system depression in Neurological), Diarrhoea +2

    Other Health Care ProfessionalSerious
  • MSK

    Dog · Reactions: Lack of efficacy (endoparasite) - heartworm

    Animal OwnerSerious
  • MSK

    Reactions: Product defect, product difficult to use/handle (see also 'Drug device difficult to use/handle'), UNPALATABLE

    Other Health Care Professional
  • MSK

    Dog · Reactions: Facial pruritus, Facial swelling (see also Skin), Anaphylaxis +3

    Other Health Care ProfessionalSerious
  • MSK

    Dog · Reactions: Lack of efficacy (endoparasite) - whipworm, Medication error NOS, Intentional misuse

    Other Health Care ProfessionalSerious
  • MSK

    Dog · Reactions: Facial swelling (see also Skin)

    Other Health Care ProfessionalSerious
  • MSK

    Dog · Reactions: Lack of efficacy (ectoparasite) - flea

    Animal Owner
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How to read this: Each report says someone told FDA an event happened while a product was used. A report does not show the product caused it, and counts rise and fall with how many people report. Data from openFDA, FDA's public API. FDA says not to rely on it to make decisions about medical care and to treat every result as unvalidated; confirm against FDA's own record and the product labeling. Not medical or legal advice.