Substances (GSRS)

(+)-KALAFUNGIN

Also: IBIOTIC PRODUCED BY STREPTOMYCES TANASHIENSIS STRAIN KALA. (1) 2H-FURO(3,2-B)NAPHTHO(2,3-D)PYRAN-2,6,11-TRIONE, 3,3A,5,11B-TETRAHYDRO-7-HYD…

chemicalUNII 7HR91T5TGW

Open FDA's page for this record

Substance class

chemical

Definition type

PRIMARY

Definition level

COMPLETE

Uuid

022d6c99-7fe7-4f8a-a76e-b2a97ec25ee9

Version

UNII

7HR91T5TGW

Codes

Uuid
835054a4-2754-47d7-a66f-de1c0553cea9
Code
11048-15-0
Type
PRIMARY
Url
https://commonchemistry.cas.org/detail?cas_rn=11048-15-0
Code system
CAS
References
b3dbdaf9-d04a-45c6-a972-883b3ff88f57, 29d536f8-a896-473d-a5be-d8e5f6962e4a
Uuid
cfa9621e-32d1-4350-90a2-544461eabbca
Code
C013079
Type
PRIMARY
Url
http://www.ncbi.nlm.nih.gov/mesh/67013079
Code system
MESH
References
b3dbdaf9-d04a-45c6-a972-883b3ff88f57
Uuid
a4add12b-95f6-4450-8b40-1dcb431751e4
Code
SUB08361MIG
Type
PRIMARY
Code system
EVMPD
References
b3dbdaf9-d04a-45c6-a972-883b3ff88f57
Uuid
f70ae9be-8e46-4692-a258-3cfc48b7888a
Code
2535
Type
PRIMARY
Url
https://extranet.who.int/soinn/mod/page/view.php?id=137&inn_n=2535
Code system
INN
References
b3dbdaf9-d04a-45c6-a972-883b3ff88f57
Uuid
bf6c1aa6-0054-4042-b3d3-a6467da2a404
Code
CHEMBL1908343
Type
PRIMARY
Url
https://www.ebi.ac.uk/chembl/compound/inspect/CHEMBL1908343
Code system
ChEMBL
References
b3dbdaf9-d04a-45c6-a972-883b3ff88f57
Uuid
d311b88c-d808-4871-8a0a-679d6cd149a1
Code
443836
Type
PRIMARY
Url
https://pubchem.ncbi.nlm.nih.gov/compound/443836
Code system
PUBCHEM
References
b3dbdaf9-d04a-45c6-a972-883b3ff88f57
Uuid
a6321a76-687e-971a-ea09-b8eec6f8795b
Code
C167025
Type
PRIMARY
Url
https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI%20Thesaurus&code=C167025
Code system
NCI_THESAURUS
References
e5cc18a8-cf10-d523-5c5f-3b9cf59edfdb
Uuid
63de8a5a-2fc4-4c92-a377-d239aa7fbb42
Code
7HR91T5TGW
Type
PRIMARY
Code system
FDA UNII
Uuid
8a1c4d15-e34f-d83f-e99c-640b21feac4c
Code
Kalafungin
Type
PRIMARY
Url
https://en.wikipedia.org/wiki/Kalafungin
Code system
WIKIPEDIA
References
e51b2ed4-cca7-e734-e903-6ba5dba52fc5
Uuid
6dc1908a-7e70-0d9d-439c-1b21c82b1c0d
Code
137443
Type
PRIMARY
Url
https://dtp.cancer.gov/dtpstandard/servlet/dwindex?searchtype=NSC&outputformat=html&searchlist=137443
Code system
NSC
References
16dc6c52-5a3b-8dfc-1848-1e3278cb2ae8
Uuid
1d91a693-9680-08d0-5800-0c5d849d4275
Code
100000082865
Type
PRIMARY
Code system
SMS_ID
References
65245576-bacf-752e-1e50-d54194072464
Uuid
77f8bb53-6d73-a293-7215-b47ef00f114f
Code
DTXSID40864305
Type
PRIMARY
Url
https://comptox.epa.gov/dashboard/chemical/details/DTXSID40864305
Code system
EPA CompTox

Relationships

Uuid
07bd9842-add2-4253-ad29-6c3b2713c178
Type
ACTIVE MOIETY
Related substance
Uuid
d50349d9-2b32-4c03-83ce-97947fc09418
Refuuid
022d6c99-7fe7-4f8a-a76e-b2a97ec25ee9
Name
Kalafungin
UNII
7HR91T5TGW
Linking ID
7HR91T5TGW
Ref pname
Kalafungin
Substance class
reference

Names

Uuid
4b30cc87-55f3-4627-bd16-885b98948cb2
Name
(+)-KALAFUNGIN
StdName
(+)-KALAFUNGIN
Type
cn
Preferred
false
Display name
false
Languages
en
References
198e3849-afb1-45a8-83a6-f66cbfaf8445, 475714f5-8b5e-4705-9405-7ed1614f1ef7
Uuid
17c457f6-020b-4451-9523-cf9019972ffb
Name
IBIOTIC PRODUCED BY STREPTOMYCES TANASHIENSIS STRAIN KALA. (1) 2H-FURO(3,2-B)NAPHTHO(2,3-D)PYRAN-2,6,11-TRIONE, 3,3A,5,11B-TETRAHYDRO-7-HYDROXY-5-METHYL-
StdName
IBIOTIC PRODUCED BY STREPTOMYCES TANASHIENSIS STRAIN KALA. (1) 2H-FURO(3,2-B)NAPHTHO(2,3-D)PYRAN-2,6,11-TRIONE, 3,3A,5,11B-TETRAHYDRO-7-HYDROXY-5-METHYL-
Type
cn
Preferred
false
Display name
false
Languages
en
References
6d609d78-757b-4f7c-b1fe-904ab84ecfc5
Uuid
ea6c9c6a-70a6-4929-8086-e033459cb3f3
Name
KALAFUNGIN [USAN]
StdName
KALAFUNGIN [USAN]
Type
cn
Preferred
false
Display name
false
Languages
en
References
bc18ca67-fb7e-4d96-8b41-b40d92aa0f89
Uuid
78587606-b3e4-4c29-bd8f-e973d15f0663
Name
Kalafungin
StdName
KALAFUNGIN
Type
of
Preferred
false
Display name
true
Languages
en
References
198e3849-afb1-45a8-83a6-f66cbfaf8445, 0d2bc242-cf94-4a1f-bf66-461ff0a73a11, bc18ca67-fb7e-4d96-8b41-b40d92aa0f89, 719cb089-dc3d-451f-a414-e0355d75bf55, 0f6acfed-b769-4805-b593-eba212003bea, 4c399105-afab-48ea-abff-a1bb44cb2a9e
Domains
drug
Name orgs
1. Uuid
  6a66324a-f259-4d4a-ac72-2713609096fb
  Name org
  INN
2. Uuid
  a7bb5e3a-c296-4c95-a957-6f81b9610ffc
  Name org
  USAN
Uuid
3d90417e-f39b-4875-84ad-4cda0e7aa62f
Name
NSC-137443
StdName
NSC-137443
Type
cd
Preferred
false
Display name
false
Languages
en
References
6d609d78-757b-4f7c-b1fe-904ab84ecfc5
Uuid
e718fc96-f390-4ae3-94ad-277729b0216d
Name
U-19,718
StdName
U-19,718
Type
cd
Preferred
false
Display name
false
Languages
en
References
6d609d78-757b-4f7c-b1fe-904ab84ecfc5
Uuid
7b9c70dd-4342-4159-a152-3df06e9d0432
Name
U-19718
StdName
U-19718
Type
cd
Preferred
false
Display name
false
Languages
en
References
198e3849-afb1-45a8-83a6-f66cbfaf8445, ca87715f-57b7-420d-878c-d1204273d57a
Uuid
829f5839-bd7b-4e43-a474-d4e70034e9fb
Name
kalafungin [INN]
StdName
KALAFUNGIN [INN]
Type
cn
Preferred
false
Display name
false
Languages
en
References
0f6acfed-b769-4805-b593-eba212003bea, 3eb7317f-5af5-4788-9c74-79e668609144

References

Uuid
719cb089-dc3d-451f-a414-e0355d75bf55
Citation
USP DICTIONARY 2009
Doc type
SRS
Public domain
true
Tags
NOMEN, PUBLIC_DOMAIN_RELEASE, AUTO_SELECTED
Uuid
198e3849-afb1-45a8-83a6-f66cbfaf8445
Citation
INN
Doc type
INN
Public domain
true
Tags
NOMEN
Uuid
6d609d78-757b-4f7c-b1fe-904ab84ecfc5
Citation
USP DICTIONARY 2010
Doc type
SRS
Public domain
true
Tags
NOMEN
Uuid
475714f5-8b5e-4705-9405-7ed1614f1ef7
Citation
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC547777/pdf/applmicro00248-0003.pdf
Url
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC547777/pdf/applmicro00248-0003.pdf
Doc type
SRS
Public domain
true
Tags
NOMEN
Uuid
0f6acfed-b769-4805-b593-eba212003bea
Citation
INN 2010
Doc type
SRS
Public domain
true
Tags
NOMEN
Uuid
bc18ca67-fb7e-4d96-8b41-b40d92aa0f89
Citation
USP DICTIONARY 2011
Doc type
SRS
Public domain
true
Tags
NOMEN
Uuid
ca87715f-57b7-420d-878c-d1204273d57a
Citation
CHEMBL
Doc type
SRS
Public domain
true
Tags
NOMEN
Uuid
b3dbdaf9-d04a-45c6-a972-883b3ff88f57
Citation
SRS CODE IMPORT
Doc type
SRS
Public domain
true
Document date
1493390842000
Tags
NOMEN
Uuid
15efb044-0367-49f8-83ae-7fe2d1461085
Citation
SRS import [7HR91T5TGW]
Url
http://fdasis.nlm.nih.gov/srs/srsdirect.jsp?regno=7HR91T5TGW
Doc type
SRS
Public domain
true
Document date
1493390842000
Tags
NOMEN
Uuid
072070cd-f1d2-447f-9e3c-67e5c367e2b4
Citation
USP DICTIONARY; http://www.ncbi.nlm.nih.gov/pmc/articles/PMC547777/pdf/applmicro00248-0003.pdf
Url
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC547777/pdf/applmicro00248-0003.pdf
Doc type
SRS
Public domain
true
Tags
NOMEN
Uuid
4c399105-afab-48ea-abff-a1bb44cb2a9e
Citation
KALAFUNGIN [INN]
Doc type
SRS_LOCATOR
Public domain
true
Uuid
0d2bc242-cf94-4a1f-bf66-461ff0a73a11
Citation
KALAFUNGIN [USAN]
Doc type
SRS_LOCATOR
Public domain
true
+6 more not shown

Moieties

Uuid
4ad9515e-0c11-4935-80ac-cdc4768b4fc2
ID
4ad9515e-0c11-4935-80ac-cdc4768b4fc2
Smiles
C[C@@H]1C2=C(C(=O)c3cccc(c3C2=O)O)[C@@H]4[C@@H](CC(=O)O4)O1
Formula
C16H12O6
Atropisomerism
No
Charge
0
Count
1
Stereochemistry
ABSOLUTE
Defined stereo
3
Ez centers
0
Molecular weight
300.2635
Optical activity
UNSPECIFIED
Stereo centers
3
Molfile
Marvin 01132103552D 22 25 0 0 1 0 999 V2000 4.8921 -4.4320 0.0000 C 0 0 2 0 0 0 0 0 0 1 0 0 5.5160 -4.9718 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1956 -5.7320 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.6222 -6.4381 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 4.3735 -5.6621 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 4.1860 -4.8586 0.0000 C 0 0 2 0 0 0 0 0 0 1 0 0 3.4634 -4.4604 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 3.4470 -3.6356 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7244 -3.2373 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7081 -2.4126 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 2.0183 -3.6641 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2958 -3.2658 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2794 -2.4410 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 0.5897 -3.6924 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 0.6061 -4.5173 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3286 -4.9155 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0348 -4.4888 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7573 -4.8871 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7737 -5.7119 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 4.1531 -3.2090 0.0000 C 0 0 1 0 0 0 0 0 0 1 0 0 4.1367 -2.3841 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 4.8757 -3.6072 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 1 2 1 0 0 0 0 6 1 1 0 0 0 0 1 22 1 6 0 0 0 2 3 1 0 0 0 0 3 4 2 0 0 0 0 5 3 1 0 0 0 0 6 5 1 6 0 0 0 6 7 1 0 0 0 0 7 8 2 0 0 0 0 18 7 1 0 0 0 0 8 9 1 0 0 0 0 8 20 1 0 0 0 0 9 10 2 0 0 0 0 11 9 1 0 0 0 0 11 12 1 0 0 0 0 17 11 2 0 0 0 0 12 13 1 0 0 0 0 12 14 2 0 0 0 0 15 14 1 0 0 0 0 16 15 2 0 0 0 0 17 16 1 0 0 0 0 18 17 1 0 0 0 0 19 18 2 0 0 0 0 20 21 1 1 0 0 0 20 22 1 0 0 0 0 M END
Count amount
Type
MOL RATIO
Average
1
Units
MOL RATIO
Uuid
fe202237-fa65-4753-802f-d0c1f77aca3f

Structure

ID: 3fd3ebb8-b6b8-48c8-9636-caed6cdd0f07
Smiles: C[C@@H]1C2=C(C(=O)c3cccc(c3C2=O)O)[C@]4([H])[C@@]([H])(CC(=O)O4)O1
Formula: C16H12O6
Atropisomerism: No
Charge: 0
Count: 1
Stereochemistry: ABSOLUTE
Defined stereo: 3
Ez centers: 0
Molecular weight: 300.2635
Optical activity: UNSPECIFIED
Stereo centers: 3
Molfile: Marvin 01132103232D 24 27 0 0 1 0 999 V2000 2.7737 -5.7119 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 2.7573 -4.8871 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0348 -4.4888 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 1.3286 -4.9155 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 0.6061 -4.5173 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 0.5897 -3.6924 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2958 -3.2658 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 1.2794 -2.4410 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 2.0183 -3.6641 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7244 -3.2373 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 2.7081 -2.4126 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 3.4470 -3.6356 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 4.1531 -3.2090 0.0000 C 0 0 2 0 0 0 0 0 0 0 0 0 4.8757 -3.6072 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 4.8921 -4.4320 0.0000 C 0 0 2 0 0 0 0 0 0 0 0 0 5.6389 -4.0816 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 5.5160 -4.9718 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.1956 -5.7320 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.6222 -6.4381 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 4.3735 -5.6621 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 4.1860 -4.8586 0.0000 C 0 0 2 0 0 0 0 0 0 0 0 0 3.5283 -5.3567 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 3.4634 -4.4604 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 4.1367 -2.3841 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 1 2 2 0 0 0 0 2 3 1 0 0 0 0 3 4 2 0 0 0 0 4 5 1 0 0 0 0 5 6 2 0 0 0 0 7 6 1 0 0 0 0 7 8 1 0 0 0 0 9 7 2 0 0 0 0 3 9 1 0 0 0 0 9 10 1 0 0 0 0 10 11 2 0 0 0 0 12 10 1 0 0 0 0 12 13 1 0 0 0 0 13 14 1 0 0 0 0 15 14 1 0 0 0 0 15 16 1 1 0 0 0 15 17 1 0 0 0 0 17 18 1 0 0 0 0 18 19 2 0 0 0 0 20 18 1 0 0 0 0 21 20 1 0 0 0 0 21 15 1 0 0 0 0 21 22 1 1 0 0 0 23 21 1 0 0 0 0 23 12 2 0 0 0 0 2 23 1 0 0 0 0 13 24 1 1 0 0 0 M END
References: 072070cd-f1d2-447f-9e3c-67e5c367e2b4, 15efb044-0367-49f8-83ae-7fe2d1461085, 3eb7317f-5af5-4788-9c74-79e668609144

Data from openFDA, FDA's public API. FDA says not to rely on it to make decisions about medical care and to treat every result as unvalidated; confirm against FDA's own record and the product labeling. Not medical or legal advice.